Promoter Associated RNA: Methods and Protocols (Methods in Molecular Biology)
Promoter Associated RNA: Methods and Protocols (Methods in Molecular Biology) by Sara Napoli
English | 28 Mar. 2017 | ISBN: 1493967142 | 300 Pages | EPUB | 3.89 MB
English | 28 Mar. 2017 | ISBN: 1493967142 | 300 Pages | EPUB | 3.89 MB
This volume is divided in four sections; covering genome wide approaches, techniques for characterize of paRNA structural features are described, selecting pa-RNA, and paRNA therapeutic potential. Chapters describe how siRNAsdirected against paRNAs can be applied in vivo to modulate transcription of important genes controlled by paRNAs. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.