Small Molecules in Hematology (Recent Results in Cancer Research) 3rd Edition, Kindle Edition
by Uwe M. Martens
English | 2018 | ISBN: 3319914383 | 294 Pages | PDF | 5 MB
by Uwe M. Martens
English | 2018 | ISBN: 3319914383 | 294 Pages | PDF | 5 MB
This book, written by respected experts, discusses in detail the latest developments in targeted therapy for hematologic malignancies using small molecules. It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed.