3D QSAR in Drug Design: Ligand-Protein Interactions and Molecular Similarity by Hugo Kubinyi
3D QSAR in Drug Design: Ligand-Protein Interactions and Molecular Similarity (Three-Dimensional Quantitative Structure Activity Relationships) by Hugo Kubinyi
English | 2002 | ISBN: 0792347900 | 428 Pages | PDF | 7 MB
English | 2002 | ISBN: 0792347900 | 428 Pages | PDF | 7 MB
Significant progress has been made in the study of three-dimensional quantitative structure-activity relationships (3D QSAR) since the first publication by Richard Cramer in 1988 and the first volume in the series. 3D QSAR in Drug Design. Theory, Methods and Applications, published in 1993. The aim of that early book was to contribute to the understanding and the further application of CoMFA and related approaches and to facilitate the appropriate use of these methods. Since then, hundreds of papers have appeared using the quickly developing techniques of both 3D QSAR and computational sciences to study a broad variety of biological problems.