Voltage-Gated Ion Channels as Drug Targets (Repost)
David J. Triggle, Murali Gopalakrishnan, David Rampe, "Voltage-Gated Ion Channels as Drug Targets"
English | 2006 | ISBN: 3527312587 | PDF | pages: 487 | 4.4 mb
English | 2006 | ISBN: 3527312587 | PDF | pages: 487 | 4.4 mb
Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology.
After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development.
For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.