Telomeres and Telomerase in Cancer
Telomeres and Telomerase in Cancer by Keiko Hiyama
English | 27 Mar. 2009 | ISBN: 1603273069 | 371 Pages | PDF | 15 MB
English | 27 Mar. 2009 | ISBN: 1603273069 | 371 Pages | PDF | 15 MB
Telomerase, an enzyme that maintains telomeres and endows eukaryotic cells with immortality, was first discovered in tetrahymena in 1985. In 1990s, it was proven that this enzyme also plays a key role in the infinite proliferation of human cancer cells. Now telomere and telomerase are widely accepted as important factors involved in cancer biology, and as promising diagnostic tools and therapeutic targets.