Statistical Mechanics and Stability of Macromolecules: Application to Bond Disruption, Base Pair Separation, Melting, and Drug
Statistical Mechanics and Stability of Macromolecules: Application to Bond Disruption, Base Pair Separation, Melting, and Drug Dissociation of the DNA Double Helix by Earl Prohofsky
English | July 28, 1995 | ISBN: 0521451841, 052167557X | 237 Pages | PDF | 5 MB
English | July 28, 1995 | ISBN: 0521451841, 052167557X | 237 Pages | PDF | 5 MB
This book develops a statistical mechanical analysis of the stability of biological macromolecules. The author's approach is valid both for the long time-scale needed for DNA bond disruption, and also for highly cooperative transitions needed to explain helix melting. Prohofsky develops a new theoretical approach for executing macromolecule calculations.