"Bioinformatics" ed. by Horacio Pérez-Sánchez

The book introduces the basic concepts and then explains its application to problems of great relevance, so both novice and expert readers can benefit from the information and research works presented here.

This book is divided into different research areas relevant in Bioinformatics such as biological networks, next generation sequencing, high performance computing, molecular modeling, structural bioinformatics, molecular modeling and intelligent data analysis.

Contents
Preface
Section 1 Analysis of Biological Networks
1 Hierarchical Biological Pathway Data Integration and Mining
2 Investigation on Nuclear Transport of Trypanosoma brucei: An in silico Approach
3 Systemic Approach to the Genome Integration Process of Human Lentivirus
Section 2 Sequence Analysis
4 SeqAnt 2012: Recent Developments in Next-Generation Sequencing Annotation
Section 3 High-Performance Computing
5 Towards a Hybrid Federated Cloud Platform to Efficiently Execute BioinformaticsWorkflows
6 Hardware Accelerated Molecular Docking: A Survey
Section 4 Molecular Modeling
7 Incorporating Molecular Dynamics Simulations into Rational Drug Design: A Case Study on Influenza a Neuraminidases
8 Using Molecular Modelling to Study Interactions Between Molecules with Biological Activity
Section 5 Structural Bioinformatics
9 On the Assessment of Structural Protein Models with ROSETTA-Design and HMMer: Value, Potential and Limitations
Section 6 Intelligent Data Analysis
10 Bacterial Promoter Features Description and Their Application on E. coli in silico Prediction and Recognition Approaches
11 Computational Approaches for Designing Efficient and Specific siRNAs
12 Novel microRNA Cloning Using Bioinformatics
13 Ensemble Clustering for Biological Datasets
14 Research on Pattern Matching with Wildcards and Length Constraints: Methods and Completeness