Chemokines And Viral Infection - Thomas E. Lane
English | 2006 | 171 Pages | ISBN: 3540292071 | PDF | 2.25 MB
English | 2006 | 171 Pages | ISBN: 3540292071 | PDF | 2.25 MB
Chemokines represent a family of over 40 small proteins that, for the most part, are secreted into the environment and function by binding to G protein-coupled receptors (GPCRs) that are expressed on numerous different cell types. When initially identified close to 30 years ago, these molecules were associated with various human inflammatory diseases and it was recognized that expression may be integral in leukocyte recruitment to inflamed tissue.
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