Tags
Language
Tags
March 2024
Su Mo Tu We Th Fr Sa
25 26 27 28 29 1 2
3 4 5 6 7 8 9
10 11 12 13 14 15 16
17 18 19 20 21 22 23
24 25 26 27 28 29 30
31 1 2 3 4 5 6

"A Master Regulator of Oxidative Stress: The Transcription Factor Nrf2" ed. by Jose Antonio Morales-Gonzalez, et al.

Posted By: exLib
"A Master Regulator of Oxidative Stress: The Transcription Factor Nrf2" ed. by Jose Antonio Morales-Gonzalez, et al.

"A Master Regulator of Oxidative Stress: The Transcription Factor Nrf2" ed. by Jose Antonio Morales-Gonzalez, Angel Morales-Gonzalez and Eduardo Osiris Madrigal-Santillan
ITexLi | 2016 | ISBN: 9535128388 953512837X 9789535128373 9789535128380 | 205 pages | PDF | 20 MB

This volume is dedicated to the efforts that various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases

Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.

Contents
Preface
1 Endogenous Antioxidants: A Review of their Role in Oxidative Stress
2 NRF2 Rewires Cellular Metabolism to Support the Antioxidant Response
3 Multiple Modes of Nrf2 Regulation and Transcriptional Response
4 Feed-Forward and Feed-Back Circuits of the NRF2/AP-1 Composite Pathway
5 Nrf2 Contributes to the Poor Prognosis and Chemoresistance
6 Possible Role of Nrf2 in Oxidative and Inflammatory Processes During Menopause
7 The Effect of Nrf2 on Diabetic Complications
8 Nrf2 Signaling: An Adaptive Response Pathway for Neurodegenerative Disorders
9 Nrf2 and Parkinson’s Disease
10 Oxidative Stress and Disease

1st true PDF with TOC BookMarkLinks