"Unraveling the Safety Profile of Nanoscale Particles and Materials: From Biomedical to Environmental Applications"

This book aims to provide the reader with a comprehensive overview of the current state of the art in nanotoxicology, featuring the most important developments and critical issues regarding the use of and exposure to nanoparticles.

As nanomaterials become increasingly present in our daily lives, pertinent questions regarding their safety arise. Nanomaterial risk assessment, as in other areas, directs much of the effort worldwide in defining guidelines that may be translated into national or international directives. Nanomaterials encompass different entities, from nanoparticles to nanostructured materials, with specific effects over cells, tissues, organisms and ecosystems depending on their biophysical characteristics. Such interactions will directly affect the impact of novel nanotechnologies.

Contents
1 Spectroscopic Insights into the Nano-Bio Interface
2 Toxicological Risk Assessment of Emerging Nanomaterials: Cytotoxicity, Cellular Uptake, Effects on Biogenesis and Cell Organelle Activity, Acute Toxicity and Biodistribution of Oxide Nanoparticles
3 Interaction of Nanoparticles with Blood Components and Associated Pathophysiological Effects
4 Cytotoxic and Antiproliferative Effects of Nanomaterials on Cancer Cell Lines: A Review
5 Nanotoxicity in Cancer Research: Technical Protocols and Considerations for the Use of 3D Tumour Spheroids
6 Applications of Fluorescent Quantum Dots for Reproductive Medicine and Disease Detection
7 Bioaccumulation and Toxic Profiling of Nanostructured Particles and Materials