"Update on Hepatitis C" ed. by Martina Smolic, Aleksandar Vcev and George Y. Wu

This book has been created by distinguished faculties from around the world to address the progress in our understanding of HCV infection and to review new treatment options, limitations, and accessibility of new therapeutic options.

In the past few years, remarkable progress has been made in our understanding of HCV biology, pathogenesis of infection, and structure-function relationships. This has led to quantum advances in clinical efficacy and tolerability. Yet, in spite of this amazing progress, there remain obstacles to widespread successful treatment. These issues include biological failures even with direct-acting agents, lack of options for individual with organ failures, drug-drug interactions, access to medications either due to lack of availability or affordability, and psychiatric and social issues. These problems are likely to remain in the future.

Contents
1 A Brief Update on the Treatment of Hepatitis C
2 Hepatitis C Virus (HCV) Treatment in Croatia: Recent Advances and Ongoing Obstacles
3 Liver Transplantation in Patients with Hepatitis C
4 Impact of HBV Infection on Outcomes of Direct-Acting Antiviral Therapy of Chronic Hepatitis C
5 Current Therapeutic Options for HCV-HIV Coinfection
6 Hepatitis C Treatment in Elderly Patients
7 Direct-Acting Antivirals (DAAs): Drug-Drug Interactions (DDIs) in the Treatment of Hepatitis C Virus (HCV)
8 Resistance to Direct-Acting Antiviral Agents in Treatment of Hepatitis C Virus Infections
9 Extrahepatic Manifestations of Hepatitis C Virus Infection
10 Hepatitis C–Associated Diabetes Mellitus
11 Neuropathological and Neuropsychiatric Determinants in HCV- Infected Patients
12 HCV and Work Ability Assessment
13 Health-Related Quality of Life in Antiviral-Treated Chronic Hepatitis C Patients
14 Pharmacogenomic Testing in the Era of Patient-Tailored HCV Treatment
15 Progress in Vaccine Development for HCV Infection
16 Approaches and Considerations for the Successful Treatment of HCV Infection
17 The Molecular Basis of Anti-HCV Drug Resistance