"Fibroblasts: Inflammation, Autoimmunity and Cancer Advances" ed. by Mojca Frank Bertoncelj, Katja Lakota

This volume presents recent advances in understanding the roles of fibroblasts and mesenchymal stem cells in tissue homeostasis and the development of human disease.

The book delves into general principles of fibroblast and mesenchymal stem cell biology and their diversity across the human body. It highlights these cells’ unique and shared characteristics across organs (e.g., vasculature, kidney, joints and exocrine glands) and specific pathologies (e.g., tissue damage, inflammation, fibrosis and cancer). A particular focus is set on the roles of fibroblasts in disease chronicity, recurrence, progression, therapeutic resistance and utilisation of the advancing knowledge for developing new therapeutic approaches within and beyond disease boundaries.

Contents
1. Organ- and Site-Specific HOX Gene Expression in Stromal Cells
2. Mesenchymal Stem/Stromal Cells and Fibroblasts: Their Roles in Tissue Injury and Regeneration, and Age-Related Degeneration
3. The Role of Fibroblasts in Atherosclerosis Progression
4. Heterogeneity of Fibroblasts in Healthy and Diseased Kidneys
5. Fibroblast-Like Synovial Cell Subsets in Rheumatoid Arthritis
6. Fibroblasts in Sjögren’s Syndrome


More : You find here