Outland (1981)

Outland is an 1981 science fiction thriller film written and directed by Peter Hyams. The movie stars Sean Connery as Marshal William T. O'Niel, Peter Boyle as Sheppard (the General Manager), Kika Markham as O'Niel's wife, and Frances Sternhagen as Dr. Lazarus.

Plot: Federal Marshal William O'Niel is assigned to a tour of duty in a titanium ore mining outpost on Jupiter's moon Io. Conditions on Io are difficult - gravity is 1/6 that of Earth with no breathable atmosphere, spacesuits are cumbersome, and miners carry their own air supply. Shifts are long but significant bonuses are paid. Sheppard (Peter Boyle) boasts that since he took over the running of Io productivity has broken all previous records. The film begins with a miner named Tarlow (John Ratzenberger) suffering an attack of the DT's ripping open his work-suit resulting in his death by decompression. Late, another miner, Cane (Eugene Lipinski), goes outside without his spacesuit, and likewise dies from decompression.
With the assistance of Dr Lazarus (Frances Sternhagen), O'Niel investigates the deaths. However, another incident happens involving a worker, Sagan (Steven Berkoff, who takes a prostitute hostage and threatens to kill her with a knife. O'Niel attempts to calm the man and by the main door, while Montone, O'Niel's sergeant (James B. Sikking), sneaks in via the air duct. Montone kills Sagan before O'Niel can talk with him.
O'Niel and Lazarus discover that all of the deaths had one thing in common, a amphetamine-type drug, allowing the miners to work continuously for days at a time. That is until they "burn out" and turn psychotic. O'Niel uncovers a drug distribution ring run by Sheppard and sanctioned by Montone.

–from wikipedia