There's a special bond between heartsick women. It may not be pretty, but it runs deep and spans continents. Though Iris (Kate Winslet) and Amanda (Cameron Diaz) live 6,000 miles apart and share little else in common—Iris is a neurotic wedding columnist who lives in a sleepy English village, Amanda is all control and California cool as a successful movie-trailer maker in L.A.—they make this connection almost instantly when they meet on a house-exchange vacation website.