Classified by their mode of action, all important classes of analgesics are presented here, including recent developments that have not yet been introduced to the market. Altogether, more than 300 compounds are described. A carefully designed layout presents the most relevant information at a glance, including compound structure, physical properties, synthesis schemes and clinical uses. Trade names for different countries are also given, allowing quick reference to compounds currently on the market. In addition to proven pain relievers, novel approaches to pain treatment are discussed and drug candidates for future therapies are presented. With its broad scope and extensive compound listings, this is a premier reference source for pain treatment by pharmacological means. A valuable resource for clinicians, drug developers and pain researchers.

Traditionally, evolutionary computing techniques have been applied in the area of data mining either to optimize the parameters of data mining algorithms or to discover knowledge or patterns in the data, i.e., to directly solve the target data mining problem. This book proposes a different goal for evolutionary algorithms in data mining: to automate the design of a data mining algorithm, rather than just optimize its parameters.

Could information and communication technology (ICT) become the transformative tool for a new style of global development? Could ICT promote knowledge-based, innovation-driven, and smart, adaptive, participatory development? As countries seek a way out of the present period of economic contraction, they are trying to weave ICT into their development strategies, in the same way organizations have learned to use ICT to transform their business models and strategies. This integration offers a new path to development that is responsive to the challenges of our times.

Polyynes: Synthesis, Properties, and Applications compiles information found scattered throughout the literature in inorganic, organic, and polymer chemistry into one cohesive volume. In addition to being a precursor of fullerenes, polyynes are one of the key precursors in the formation of soot and carbon dust, or elemental carbon in the galaxy, and their properties can be linked to interstellar band phenomena and other astrophysical behavior. More than 1,000 organic molecules produced by plants, fungi, and other microorganisms are also classified as polyynes, playing a biological role in nature that may be used in the treatment of diseases as antibiotics, anticancer, or anti-infective agents. Polyynes: Synthesis, Properties, and Applications covers breakthrough discoveries, particularly the simplified synthesis of polyynes in solution stabilized by using appropriate end groups and carbon films achieved using chemical, electrochemical, and other sophisticated techniques.

1Password is a password manager that uniquely brings you both security and convenience. It is the only program that provides anti-phishing protection and goes beyond password management by adding web form filling and automatic strong password generation. All your confidential information, including passwords, identities, and credit cards, is kept secure in one secure place using a highly encrypted keychain.