Statistical Monitoring of Clinical Trials: Fundamentals for Investigators by Lemuel A. Moyé
Statistical Monitoring of Clinical Trials: Fundamentals for Investigators by Lemuel A. Moyé
English | Nov. 16, 2005 | ISBN: 0387277811 | 269 Pages | PDF | 1 MB
English | Nov. 16, 2005 | ISBN: 0387277811 | 269 Pages | PDF | 1 MB
Statistical Monitoring of Clinical Trials: Fundamentals for Investigators introduces the investigator and statistician to monitoring procedures in clinical research. Clearly presenting the necessary background with limited use of mathematics, this book increases the knowledge, experience, and intuition of investigations in the use of these important procedures now required by the many clinical research efforts.
The author provides motivated clinical investigators the background, correct use, and interpretation of these monitoring procedures at an elementary statistical level. He defines terms commonly used such as group sequential procedures and stochastic curtailment in non-mathematical language and discusses the commonly used procedures of Pocock, O’Brien–Fleming, and Lan–DeMets.