Design of Controlled Release Drug Delivery Systems (McGraw-Hill Chemical Engineering) by Xiaoling Li

The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.

Contents: Pharmacokinetics and Pharmacodynamics: Rationales for Design of Controlled Release Drug Delivery Systems * Barriers to Drug Delivery: Physiological and Biochemical Aspects * Prodrugs * Drug Conjugates 1: Transporter Surrogates * Drug Conjugates 2: Polymer Conjugates * Diffusion Controlled Systems * Dissolution Controlled Systems * Osmotic Controlled Systems * Ion Exchange Controlled Systems * Biodegradable/Erodible Systems * Infusion Pumps * Inhalation Systems • Gastric Retention Systems * Nanoparticulates * Lipid Based Delivery Systems * Microelectronics/Microfabrication Related Systems * Solid Freeform Fabrication: Three-Dimensional Printing * Targeted Delivery 1: Receptor and Antibody Cognizant * Targeted Delivery 2: Physical Approaches * Carrier and Vector Mediated Delivery Systems for Biological Macromolecules