Gasotransmitters in Organ Transplantation
Gasotransmitters in Organ Transplantation: A New Era in Transplant Medicine
English | 2024 | ISBN: 303148066X | 317 Pages | PDF EPUB (True) | 10 MB
English | 2024 | ISBN: 303148066X | 317 Pages | PDF EPUB (True) | 10 MB
This book covers recent pre-clinical and clinical developments in gasotransmitters (nitric oxide, carbon monoxide and hydrogen sulfide) in all transplantable solid organs – kidney, heart, lung, liver, pancreas and intestine. Gasotransmitters are a class of small endogenously produced gaseous signaling molecules that play important roles in cellular homeostasis and impact physiological and pathophysiological situations. Recently, these gasotransmitters have emerged as potent cytoprotective mediators, possessing therapeutic properties that enable them exhibit their intracellular signaling functions. Hence, alterations in their physiological levels have been associated with various pathologies including cold ischemia-reperfusion injury (IRI) in organ transplantation.