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    3. Thymic Development and Selection of T Lymphocytes (Repost)

    Thymic Development and Selection of T Lymphocytes (Repost)

    Posted By: AvaxGenius
    Date: 7 Aug 2022 15:43:03
    Thymic Development and Selection of T Lymphocytes (Repost)

    Thymic Development and Selection of T Lymphocytes by Thomas Boehm, Yousuke Takahama
    English | PDF | 2014 | 134 Pages | ISBN : 3642402518 | 2.2 MB

    The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
    UPWARDS