A Means to an End: The Biological Basis of Aging and Death by William R. Clark
English | 1 Feb. 1999 | ISBN: 0195125932, 0195153758 | 251 Pages | PDF | 3 MB
English | 1 Feb. 1999 | ISBN: 0195125932, 0195153758 | 251 Pages | PDF | 3 MB
This work covers ageing from a fundamental cell biological perspective. The evolution and developmental genetics of senescence are explained clearly. All the various theories of ageing - the Hayflick limit and telomeric shortening as a possible biological clock, the impacts of somatic mutations, oxidative stress, accumulation of waste materials in cells with age - are explained and critically assessed.