Progress in PET Radiopharmaceuticals

by Sushil K. Sharma (Author)

This book describes classical and potential PET radiopharmaceuticals (PET-RPs) which can provide high-resolution 5D images in-vivo to simultaneously diagnose and treat the patient. This novel (theranostic) approach avoids futile therapies, unnecessary radiation exposure, and saves a lot of time, money, and energy.

The most significant challenge is to properly build Cyclotron & PET RPs labs. Existing books offer insufficient knowledge to accomplish the full potential of these highly specialized, expansive, and sophisticated labs, demanding in-depth knowledge, confidence, cooperation, a mutual understanding, adjustment, time management, team effort, patience, resilience, and dedication.

A systematic approach is provided to integrate Cyclotron and PET-RPS labs, run the cyclotron properly, resolve technical problems efficiently, and maintain quality control (QC) without being exposed to an unnecessary radiation hazard due to repetitive run failure, innocence, ignorance, negligence, misconception, misunderstanding, and/or overconfidence. Described QC experiments can be globally reproduced in other labs.

The contents provided are thought-provoking and motivate cyclotron engineers, basic scientists, radiopharmaceutical scientists, radiopharmacists, and physicians to develop novel PET-RPs in this challenging the era of Nanotheranostics.

The most recent knowledge of potential PET-RPs in the early theranostics of cancer, cardiovascular diseases, neurodegenerative diseases, drug addiction, obesity, neurobehavioral disorders, rheumatoid arthritis, and chronic inflammatory illnesses is provided with currently limited treatment options.

This unique, informative, and timely released book will act as a helpful guide; it is an applied textbook for basic biomedical students, scientists, researchers, teachers, doctors, administrators, and affiliated staff involved in current and future development of novel PET-RPs to accomplish personalized theranostics.

Book Review
“This book is a thoroughly compiled addition to the existing literature in the field of radiopharmaceuticals, their quality control and personalized theranostics in various disease conditions. It will serve as a reference book for both basic scientists and clinicians as well as for the new comers in this field undergoing training. PET imaging is a very specialized and technologically advanced area that provides spatiotemporal information and significantly contributes to decision making in complex disease conditions like cancer, brain disorders and cardiovascular problems. Author of this book, Professor Sushil K. Sharma, an expert in the field of neurosciences and medical radiopharmaceutical technology has shared his own personal experience, elaborated findings of others and given a lucid account of fundamentals of PET radiopharmaceuticals and their applications to both basic and clinical research.” - Vijay L. Kumar, Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India



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