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    3. Cytotoxic Payloads for Antibody–Drug Conjugates

    Cytotoxic Payloads for Antibody–Drug Conjugates

    Posted By: interes
    Date: 11 Oct 2020 23:44:24
    Cytotoxic Payloads for Antibody–Drug Conjugates

    Cytotoxic Payloads for Antibody–Drug Conjugates (ISSN) by Paul J M Jackson and David E Thurston
    English | Jul 15, 2019 | ISBN: 1788010779 | 502 pages | PDF | 35 MB

    The antibody–drug conjugates (ADCs) field is one of the fastest growing areas of drug discovery and represents a large body of research. ADCs deliver a cytotoxic payload, a key component of the overall ADC design, specifically to cancer cells by attaching it to an antibody targeted to antigens on the cell surface. This book discusses the range of payloads used to date along with their advantages and disadvantages, and describes novel payloads at the research stage that may be used clinically in the near future.

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