Epigenetic Targets in Drug Discovery (repost)
Epigenetic Targets in Drug Discovery (Methods and Principles in Medicinal Chemistry) by Wolfgang Sippl, Manfred Jung, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
English | 2009-08-11 | 314 Pages | ISBN: 3527323554 | PDF | 4 MB
English | 2009-08-11 | 314 Pages | ISBN: 3527323554 | PDF | 4 MB
Fueled by the expertise of a team of international specialist authors, this first reference on the booming topic covers everything a drug researcher needs to know about targeting epigenetic mechanisms of disease.
The first part of the book surveys current methodologies for finding and validating drug candidates that act via epigenetic mechanisms. The second part systematically surveys known and suspected drug targets within the epigenetic machinery, including the discovery and development of vorinostat, the first marketed epigenetic drug.