Oral Bioavailability and Drug Delivery: From Basics to Advanced Concepts and Applications (Wiley Series in Drug Discovery and Development) by Ming Hu, Xiaoling Li
English | February 13, 2024 | ISBN: 1119660653 | 928 pages | PDF | 21 Mb
English | February 13, 2024 | ISBN: 1119660653 | 928 pages | PDF | 21 Mb
ORAL BIOAVAILABILITY AND DRUG DELIVERY
Improve the performance and viability of newly-developed and approved drugs with this crucial guide
Bioavailability is the parameter which measures the rate and extent to which a drug reaches a user’s circulatory system depending on the method of administration. For example, intravenous administration produces a bioavailability of 100%, since the drugs are injected directly into the circulatory system; in the case of oral administration, however, bioavailability can vary widely based on factors which, if not properly understood, can result in a failure in drug development, adverse effects, and other complications. The mechanics of oral bioavailability are therefore critical aspects of drug development.
Oral Bioavailability and Drug Delivery provides a comprehensive coverage of this subject as well as its drug development applications. Beginning with basic terminology and fundamental concepts, it provides a thorough understanding of the challenges and barriers to oral bioavailability as well as the possibilities for improving this parameter. The resulting book is an indispensable tool for drug development research.
Oral Bioavailability and Drug Delivery readers will also find:
- Discussion questions in many chapters to facilitate comprehension
- Detailed discussion of topics including dissolution, absorption, metabolism, and more
- Real-world examples of methods in actions throughout
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