"Advances in Osteoporosis" ed. by Yannis Dionyssiotis

The drugs are an essential element of the therapy and this issue is analyzed extensively in this book. Some novel pathophysiological mechanisms are presented in this book. The book includes chapters from researchers from all over the world.

A balanced regulation of bone formation and resorption in the healthy individual is required for a healthy bone. On the other side, there are many factors which can lead to alterations in bone density and microarchitecture. Menopause is a condition which can increase the remodeling process in favor of resorption.
Moreover, there are also some diseases, i.e. chronic kidney bone disease, that increase the possibility of fractures and the subsequent disability leading to increased mortality.

Contents
Preface
1 Densitometric Diagnosis Of Osteoporosis
2 Estrogen Deficiency and Osteoporosis
3 Genetic Disorders Associated with Osteoporosis
4 Homocysteine and Leptin in the Pathogenesis of Osteoporosis — Evidences, Conflicts and Expectations
5 Biological Effects of Skeletal Renin-Angiotensin System in Osteoporosis
6 Pharmacological Treatment of Osteoporosis
7 Management of Osteoporosis in Chronic Kidney Diseases
8 Hydrophilic Matrix Tablets Based on Carbopol for Improving the Oral Bioavailability of Sodium Alendronate — In vitro and In vivo Assessment