"Hepatitis C: From Infection to Cure" ed. by Imran Shahid

This book pragmatically overviews the intricate interplay between viral and host factors during hepatitis C virus infection progression, as well as other hepatitis C-associated clinical implications.

The propagation of hepatitis C from acute to chronic infection and afterward to end-stage liver diseases (hepatic fibrosis, cirrhosis, and hepatocellular carcinoma) involves a highly orchestrated series of molecular and cellular events, including a plethora of genes and cell signaling cascades. The treatment paradigms was revolutionized after the development and approval of all oral interferon-free direct-acting antivirals achieving higher sustained virologic response rates in treated individuals. Hepatitis C - From Infection to Cure also provides up-to-date information about hepatitis C cures for clinicians, physicians, and healthcare providers with an ample understanding of the current treatment horizon, as well as other investigational and emerging treatment strategies. The authors with their valuable scientific contributions belong to many eminent institutes around the world and are much experienced in hepatitis C virology, pathology, and therapeutics.

Contents
1. Current and Emerging Anti-Hepatitis C Regimens: Hope or Hype
2. Hepatitis C Virus and Inflammation
3. HCV Lymphotropism and Its Pathogenic Significance
4. The Molecular Background Associated with the Progression of Hepatitis C to Hepatocellular Carcinoma
5. Micro-RNA in Hepatocellular Carcinoma - Related Hepatitis C Virus Patients in Correlation to Disease Progression
6. Metabolic Factors and Their Influence on the Clinical Course and Response to HCV Treatment
7. Periodontal Implications of Hepatitis C Infection
8. Hepatitis C: Host and Viral Factors Associated with Response to Therapy and Progression of Liver Fibrosis
9. Safety, Tolerability, and Associated Side Effects of Direct- Acting Antivirals
10. Hepatitis C Viral Dynamics Using a Combination Therapy of Interferon, Ribavirin, and Telaprevir: Mathematical Modeling and Model Validation


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