"Hypoxia and Human Diseases" ed. by Jing Zheng and Chi Zhou

The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders.

This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.

Contents
Preface
1 The Multifaceted Role of Hypoxia‐Inducible Factor 1 (HIF1) in Lipid Metabolism
2 Hypoxic Upregulation of ARNT (HIF-1β): A Cell-Specific Attribute with Clinical Implications
3 The Hypoxia-Reoxygenation Injury Model
4 Vascular Smooth Muscle as an Oxygen Sensor: Role of Elevation of the [Na+]i/[K+]i
5 Hypoxia in Mesenchymal Stem Cell
6 Cardiovascular Adaptation to High-Altitude Hypoxia
7 Arterial Oxygen Saturation During Ascent to 5010 m: Heart Rate and AMS Scores
8 Hypoxia-Induced Molecular and Cellular Changes in the Congenitally Diseased Heart: Mechanisms and Strategies of Intervention
9 Adaptations to Chronic Hypoxia Combined with Erythropoietin Deficiency in Cerebral and Cardiac Tissues
10 Hypothermia in Stroke Therapy: Systemic versus Local Application
11 Hypoxia and Pulmonary Hypertension
12 Stage-Specific Effects of Hypoxia on Interstitial Lung Disease
13 Hypoxia Modulates the Adenosinergic Neural Network
14 The HIF System Response to ESA Therapy in CKD‐Anemia
15 Role of the Hypoxia-Inducible Factor in Periodontal Inflammation
16 Interplay between Hypoxia, Inflammation and Adipocyte Remodeling in the Metabolic Syndrome
17 Epigenetic Programming of Cardiovascular Disease by Perinatal Hypoxia and Fetal Growth Restriction
18 The Critical Role of Hypoxia in Tumor-Mediated Immunosuppression
19 Cross‐Talk Between Hypoxia and the Tumour via Exosomes
20 A Novel Hypoxia Imaging Endoscopy System
21 Hypoxia and its Emerging Therapeutics in Neurodegenerative, Inflammatory and Renal Diseases