"Mechanisms of Neuroinflammation" ed. by Gonzalo Emiliano Aranda Abreu

This book explains how the neuronal cells become swollen at the moment of the blood-brain barrier disruption and how they lose their immunological isolation.

A cascade of cytokines and immune cells from the bloodstream enters the nervous system, inflaming neurons and activating the glia. This produces a neuroinflammatory process that can generate different neurodegenerative diseases. Better understanding of mechanisms that are activated at the time when the damage to the brain occurs could lead to the development of suitable therapies that revert the neuronal inflammation and thus prevent further damage to the nervous system.


Contents
1 Reducing Neuroinflammation in Psychiatric Disorders: Novel Target of Phosphodiesterase 4 (PDE4) and Developing of the PDE4 Inhibitors
2 Neuroinflammation and Neurotransmission Mechanisms Involved in Neuropsychiatric Disorders
3 Comprehensive Overview of Alzheimer’s Disease Neurodegeneration, from Amyloid-β to Neuroinflammatory Modulation
4 Neuroimmune Dynamics in Alzheimer’s Disease Progression
5 Interleukin 1 Receptor and Alzheimer’s Disease-Related Neuroinflammation
6 A Review of Neuroinflammatory Mechanisms in Ischemic Stroke: Background and Therapeutic Approaches
7 On Overcoming Barriers to Application of Neuroinflammation Research
8 The Role of NO/cGMP Signaling on Neuroinflammation: A New Therapeutic Opportunity
9 Roles of Pro- and Anti-inflammatory Cytokines in Traumatic Brain Injury and Acute Ischemic Stroke
10 Role of Kynurenine Pathway in Glioblastoma
11 Neuroinflammatory Signals during Acute and Chronic Liver Diseases