"Mitochondria and Brain Disorders" ed. by Stavros Baloyannis

This volume is dedicated to efficient treatment of mitochondrial dysfunction, it would open new horizons in the therapeutic perspectives of a substantial number of inflammatory and degenerative neurological disorders.

The mitochondrion is a unique and ubiquitous organelle that contains its own genome, encoding essential proteins that are major components of the respiratory chain and energy production system. Mitochondria play a dominant role in the life and function of eukaryotic cells including neurons and glia, as their survival and activity depend upon mitochondrial energy production and supply. Besides energy production, mitochondria also play a vital role in calcium homeostasis and may induce apoptosis by excitotoxicity. Mitochondrial dysfunction is related to common neurological diseases, such as Parkinson's disease, Alzheimer's disease, Friedreich's ataxia, Huntington's disease, and Multiple Sclerosis. An efficient treatment of mitochondrial dysfunction would open new horizons in the therapeutic perspectives of a substantial number of inflammatory and degenerative neurological disorders.

Contents
1.Introductory Chapter: Mitochondrial Alterations and Neurological Disorders
2.Pathology Associated with Hormones of Adrenal Cortex
3.PET Imaging of Mitochondrial Function in the Living Brain
4.Mitochondrial Proteomic and Molecular Network Alterations in Human Ovarian Cancers
5.Mitochondrial Dysfunction as a Key Event during Aging: From Synaptic Failure to Memory Loss
6.Coenzyme Q 10 and L-Carnitine Disturbances in Children with Mitochondrial Diseases