"Peripheral Membrane Proteins" ed. by Shihori Tanabe
ITExLi | 2018 | ISBN: 1789235138 9781789235135 178923512X 9781789235128 | 123 pages | PDF | 9 MB
ITExLi | 2018 | ISBN: 1789235138 9781789235135 178923512X 9781789235128 | 123 pages | PDF | 9 MB
This book intends to provide a comprehensive overview of the features and signaling of peripheral membrane proteins, which includes the molecular structure and interaction. The insights into membrane proteins associated with diseases and therapeutics and the effects of drugs and chemicals are also discussed in this book.
The peripheral membrane proteins transduce the extracellular signaling into the cells. The peripheral membrane proteins include the G protein-coupled receptors, receptor tyrosine kinases, channels and transporters. The signals, which are transduced via the peripheral membrane proteins, activate several pathways including G protein signaling, MAPK signaling, TNF signaling, TGF? signaling, Wnt signaling and Hedgehog signaling. The peripheral membrane proteins transduce the signaling from the extracellular ligands into the cells.
Contents
1 Introductory Chapter: Invitation for Peripheral Membrane Proteins
2 The Function of Fission Yeast Rho1-GEFs in the Control of Cell Growth and Division
3 Biosensing Techniques in Yeast: G-Protein Signaling and Protein-Protein Interaction Assays for Monitoring Ligand Stimulation and Oligomer Formation of Heterologous GPCRs
4 The Function of Rab35 in Development and Disease
5 Aberrant SGK1 Transcription in LNCaP: A Novel Feed-back Mechanism of TGF-beta1 Regulation in Prostate Carcinogenesis
6 Rapid Endosomal Recycling
7 Folding and Binding Properties of Human Complement Receptor Type 1 Extracellular Domain
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