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    ABC Transporters - 40 Years on

    Posted By: AvaxGenius
    ABC Transporters - 40 Years on

    ABC Transporters - 40 Years on by Anthony M. George
    English | PDF | 2016 | 384 Pages | ISBN : 3319234757 | 8.1 MB

    This book provides new structural, biochemical, and clinical information on ABC transporters. The authors explore and describe the state of the art of research, knowledge, and prospects for the future for this important family of proteins. The first ABC transporter was discovered in 1973 and was named P-glycoprotein. It elicits resistance to cytotoxic drugs, chiefly in human tumours, within which chemotherapy failure is observed in about 50% of cases. Together with its complex pharmacology, and even a suspected role in Alzheimer’s disease, this ABC transporter still eludes a clinical solution to its multidrug resistance property. ABC transporters are integral membrane active proteins and they belong to one of the largest protein families across all species. Their myriad roles encompass the import or export of a diverse range of allocrites, including ion, nutrients, peptides, polysaccharides, lipids, and xenobiotics. They are of major medical importance with many members elaborating multidrug resistance in bacteria, fungi, yeast, parasites, and humans. Other ABC transporters are involved in a number of inherited diseases, including cystic fibrosis, macular degeneration, gout, and several other metabolic disorders.

    Beta-Lactam Resistance in Gram-Negative Bacteria: Threats and Challenges

    Posted By: AvaxGenius
    Beta-Lactam Resistance in Gram-Negative Bacteria: Threats and Challenges

    Beta-Lactam Resistance in Gram-Negative Bacteria: Threats and Challenges by Mohammad Shahid
    English | PDF,EPUB | 2022 | 330 Pages | ISBN : 9811690960 | 12.4 MB

    This timely book discusses antimicrobial drug resistance, specifically, the resistance against the beta-lactam class of antibiotics by Gram-Negative bacteria. The book is broadly divided into five sections. The first section describes the underlying mechanisms of antimicrobial resistance in Gram-negative bacteria. It gives an insight into the beta-lactamases, their types, classification, inhibitors, etc.

    Introduction to Basics of Pharmacology and Toxicology: Volume 2

    Posted By: AvaxGenius
    Introduction to Basics of Pharmacology and Toxicology: Volume 2

    Introduction to Basics of Pharmacology and Toxicology Volume 2 : Essentials of Systemic Pharmacology : From Principles to Practice by Abialbon Paul
    English | PDF,EPUB | 2021 | 1156 Pages | ISBN : 9813360089 | 89.2 MB

    This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems.

    Ethics and Drug Resistance: Collective Responsibility for Global Public Health

    Posted By: roxul
    Ethics and Drug Resistance: Collective Responsibility for Global Public Health

    Euzebiusz Jamrozik, "Ethics and Drug Resistance: Collective Responsibility for Global Public Health "
    English | ISBN: 3030278735 | 2020 | 465 pages | EPUB, PDF | 1065 KB + 5 MB

    Pathogenicity and Drug Resistance of Human Pathogens: Mechanisms and Novel Approaches

    Posted By: roxul
    Pathogenicity and Drug Resistance of Human Pathogens: Mechanisms and Novel Approaches

    Saif Hameed, "Pathogenicity and Drug Resistance of Human Pathogens: Mechanisms and Novel Approaches"
    English | ISBN: 9813294485 | 2019 | 404 pages | EPUB, PDF | 16 MB + 7 MB