Based on Anne Frank's diary, and the stage play that was adapted from it: In Nazi-occupied Holland, Otto Frank and his family have decided to go into hiding, because of the increasing persecutions against Jews. The businessman Kraler and his assistant Miep prepare a hiding place in the rooms above their place of business, and arrange for the Franks and another family, the Van Daans, to stay there. Later on, they are joined by the dentist Dussel. Together, they try to avoid detection while hoping for Holland to be liberated by the Allies, but even meeting basic needs can become a challenge, and even minor incidents could present a grave risk.

As Paleoclimatologist named Jack Hall is in Antartica, he discovers that a huge ice sheet has sheared off. But what he does not know is that this event will trigger a massive climate shift that will affect the world population. Meanwhile, his son Sam is with friends in New York to attend an event.

A missile disappears in Iran, but the CIA has other problems: the heir to an Emirate gives an oil contract to China, cutting out a US company that promptly fires its immigrant workers and merges with a small firm that has landed a Kazakhstani oil contract. The Department of Justice suspects bribery, and the oil company's law firm finds a scapegoat. The CIA also needs one when its plot to kill the Emir-apparent fails. Agent Bob Barnes, the fall guy, sorts out the double cross. An American economist parlays the death of his son into a contract to advise the sheik the CIA wants dead. The jobless Pakistanis join a fundamentalist group. All roads start and end in the oil fields.

Out on the ocean, a ship of doctors and nurses is traveling to the poorest of the poor living in West Africa. It carries life saving medical services for people who have none: children who suffer with terrible leg deformities, women outcast from their communities by birthing fistulas, vast tumors of all shapes and sizes which afflict the unlucky. With no medical help, sufferers must survive the best they can - unless the ship is in port.

At Mount Holliston, snowboarders Dan Walker, his girlfriend Parker O'Neil and his best friend Joe Lynch don't have enough money to buy lift tickets. Parker bribes Jason, a lift-worker, with one hundred dollars. When the system is nearing closure, they force Jason to let them have one last pass. However, Jason needs to resolve a problem and his colleague misunderstands his instructions and stops the lift. The trio of skier and snowboarders gets stranded on the chairlift near the top of the mountain. When they see that the lights of the ski resort had been turned off, they need to make a choice: leave the chairlift or freeze to death.

At 35, Tripp has an interesting job, a hip car, a passion for sailing, and a great house - trouble is, he lives with his parents. They want him out, so they hire Paula, an "interventionist," who has a formula in these cases: chance encounter, get him to ask her out, involve him in a trauma, meet his friends and get their nod, delay sex, have him teach her something, then launch him. It's worked up to now, but this gets complicated when Tripp thinks she's getting too serious and one of his pals is attracted to Paula's deadpan, semi-alcoholic roommate, who's plagued by a mockingbird. Too many secrets may scrub the launch, and what if Paula really likes him? Who can intervene then?