"Non-Proteinogenic Amino Acids" ed. by Nina Filip, Cristina-Elena Iancu
ITExLi | 2018 | ISBN: 178984729X 9781789847291 1789847281 9781789847284 183881597X 9781838815974 | 57 pages | PDF | 5 MB
ITExLi | 2018 | ISBN: 178984729X 9781789847291 1789847281 9781789847284 183881597X 9781838815974 | 57 pages | PDF | 5 MB
In this book are presented both methods for the determination of homocysteine and its involvement in human pathology.
The first description of homocysteine (Hcy), a non-proteinogenic amino acid, was introduced in a case study more than 70 years ago. In recent years, numerous studies have shown a positive correlation between serum levels and various diseases, especially vascular pathology. Vitamins B6, B12, and folic acid play a major role in controlling homocysteine levels. Homocysteine levels can be taken as an early indicator for the detection of cardiovascular diseases because Hcy levels increase after a myocardial infarction or stroke.
Contents
1. Introductory Chapter: General Aspects Regarding Homocysteine
2. HPLC Analysis of Homocysteine and Related Compounds
3. Is Homocysteine a Marker or a Risk Factor: A Question Still Waits for an Answer
4. How Homocysteine Modulates the Function of Osteoblasts and Osteocytes
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