This book provides a unique frame work for examining acute lung syndromes that arise from hematologic disorders or is defined by a hematologic abnormality as a key feature. Acute lung processes arising from hematologic disorders can present as life-threatening conditions, and as such, the pulmonary physician or critical care physician are often directly involved in care or called upon to provide expertise. Chapters are organized into three sections, each with an emphasis on pathogenesis and current understanding of mechanisms. The text begins with the central theme of the lungs as the direct interface between the external environment and blood, description of individual components of the hematopoietic system, their function and relevance to the lungs. The second section outlines both benign and malignant primary hematologic disorders that can lead to acute pulmonary manifestations. The final section focuses on acute lung syndromes stemming from complications of transfusion and treatment. Chapters are presented in an easy-to-access format, providing information on diagnosis, management, and outcomes. This is a valuable resource for pulmonary fellows in training, pulmonologists, critical care physicians, and physicians involved in caring for patients in the ICU.

This book offers a comprehensive overview of alpha-1 antitrypsin deficiency, an inherited condition that leads to lung disease in adults and liver disease in adults and children and is associated with chronic obstructive lung disease in adults. While it is a rare condition, the mechanisms underlying the clinical manifestations of this deficiency have been largely clarified. Treatment, however, is available only for the lung disease that arises from the condition, thus necessitating continued research into new and alternative therapeutic solutions. The book discusses the biology of alpha-1 antitrypsin, protein misfolding and polymerization, and diagnosis and treatment of alpha-1 antitrypsin deficiency and its associated diseases. It concludes with a discussion of rare disorders linked to alpha-1 antitrypsin deficiency and the role of healthcare organizations in the treatment of these diseases. Written for pulmonary clinicians and scientists, Alpha-1 Antitrypsin: Role in Health and Disease is a valuable resource that sheds light on this rare disease.

This book offers an in-depth and up-to-date review of bronchiectasis. Bronchiectasis is a broadly heterogenous disease with a variety of etiologies and disease phenotypes and endotypes. To comprehensively and adequately address bronchiectasis, all these aspects need to be considered, which is not always the case in the current literature. Throughout this book, expert authors discuss the epidemiology, etiology, clinical management and clinical trials to give the reader greater context and tools to care for their patients. Chapters include coverage of environmental and infectious causes of bronchiectasis, radiographic phenotyping, diagnosing, and monitoring of bronchiectatic diseases, and host directed therapy. This is an ideal guide for pulmonologists and trainees caring for patients with bronchiectasis.

This volume is dedicated to new analytical techniques, which greatly simplified the quantitation of many trace elements and considerably extended their detection range. In this context, the development of reproducible and accurate techniques for trace element analysis in different media using spectroscopic instrumentation is continuously updated.

by Delthia Ricks (Author)
The COVID-19 pandemic has staked its claim as the deadliest worldwide respiratory disease outbreak in over 100 years

This book serves as the primary reference for precision medicine in the fields of pulmonary, critical care and sleep medicine by documenting principles written by experts in several aspects of precision medicine. It combines fundamental concepts of the field with state-of-the-art studies and how they translate into individual preventive, diagnostic and therapeutic plans.